Streetwise Professor

May 19, 2025

A Few Components of the Trump Gamma Trade

Filed under: Economics,Politics,Regulation — cpirrong @ 12:09 pm

“Haven’t seen you around recently. So what’s up?”, says you. “Same old, same old: Just the Trump gamma trade”, says I. (After the 2016 election I wrote that a Trump presidency meant you should be long gamma. That’s even more true after 2024).

So the tariff two step has continued. Trump caved! Xi caved!

Whatever. If you believe (as I said literally on day 1, AKA Liberation Day) that the initial tariff salvoes were a negotiating tactic, the outcome was expected. Make maximalist demands, negotiate down from there.

NB. The negotiations continue. This ain’t over.

I only remark that if Trump had announced the current (interim) levels on 2 April, the frenzy would have no doubt been about the same as it was with the 125 percent charge for China, etc. But now these levels (30 to 50+ percent, depending on how you calculate) are greeted with a huge sigh of relief and a complete reversal of the market selloff that greeted the initial announcement. In other words, if you panicked, you were played.

Another fairly recent development has been the prescription drug EO. The initial (over-) reaction has been that Trump is ordering price controls. Well, not exactly. (The irony here is that the right has been critical, and the left hypocritically silent, because Trump).

At the outset, let me say that (as I will explain in more detail below) I am ambivalent about overall policy framework. But the reason I say there has been an overreaction is that all it is right now is just a framework. The only real action item is a direction that HHS formulate a set of rules that will require pharmaceutical companies to allow consumers to purchase directly from them at “most favored nation” (“MFN”) prices. We know how long the rule process takes. We also know that the devil will be in the details of the rule, and those details will be determined in a highly politicized environment where the regulated have a huge say, so it is impossible to draw conclusions about what effects it will actually have, or when it will have them.

Trump’s basic attack–that comparisons between US and foreign prices for the same drugs prove that Americans are being ripped off–is an old one, and ironically was a talking point of Hillary in 1992-1993. The policy piece I wrote in 1993 (“Political Rhetoric and Stock Price Volatility”) addressed this very issue. (Ironically, it was that piece that put my on Hillary’s Hit List, the figurative one at least; it didn’t cost me my life, but did jeopardize my career).

Defenders of this pricing structure claim that it is purely economic conduct by pharma, specifically, price discrimination. More elastic demanders pay a lower price than inelastic American ones.

Yes, this might be why some drugs are dirt cheap in Africa, say, but it is hardly the entire story. Drug companies have to offer big price cuts to high income countries (European countries, Canada, etc.) whose demand is likely about as inelastic as the US’s, so that their national health services will buy them. One interpretation is that these countries are free riding off the innovation paid for by US consumers who pay full fare.

Which raises another issue. Presumably Trump believes that the MFN rule he has outlined will result in drug makers dropping US prices to match foreign ones. But no doubt some of the movement will go in the other direction–the companies will raise prices in other markets, and in some cases will decide to forego some smaller markets altogether rather than have their prices drive those in the really big market. Meaning that the ultimate effect on US price levels is hard to determine.

One part of the EO actually addresses this issue. It directs the U.S. Trade Representative and the Secretary of Commerce to ensure that foreign governments are not taking actions to undercut US prices. (The order incorrectly states that such undercutting raises US prices). That is, this is really a trade issue, and in particular a non-tariff barrier/IP expropriation issue that is more properly addressed in the context of trade negotiations.

The EO–as is the case with most policy proposals directed at drug prices–ignores the real drivers: patent protection, R&D costs, and third-party payments. If you think drug prices are too high, that is, the prices are in excess of what is required to induce the efficient level of innovation, then go after these issues. Examine whether drug patent protection should be attenuated (not extended as it was in recent years). Whether regulatory burdens unnecessarily inflate R&D costs. Cross-country price comparisons tell you nothing about these issues.

Insofar as third-party payment is concerned, the EO does address that issue to some degree. Specifically, the direct purchase option (subject to MFN provisions) is intended to “cut out the middleman,” namely, the Pharmaceutical Benefit Mangers (Caremark Rx, LLC (CVS), Express Scripts, Inc. (ESI), and OptumRx, Inc. (OptumRx) being the Big 3). These are accused of (a) charging high markups on drugs, and (b) excluding many drugs from their formularies.

The first issue is again related to relative prices, not price levels. That is, it is really about who captures the monopoly rent that ultimately derives from patent protection. The main concern is double marginalization–the inefficiency that results from back-to-back monopolists. Double monopolization can lead to prices that are higher than monopoly prices. Another concern could be that the PBMs exercise monopsony power, thereby reducing the returns to R&D and suppressing innovation. (This makes PBMs analogous to foreign governments).

I am always skeptical of “cut out the middleman” arguments because they ignore Chesterton’s Fence: why do the middlemen exist in the first place? If they bring cost but no benefit, how can they survive?

I don’t know the answer in this case. But (a) I am sufficiently skeptical based on long experience so as to not fully credit the seductive cut-out-the-middleman argument (which is almost always wrong, unless the middleman is a government creation), and (b) relatedly, would not be surprised if PBMs are ultimately the creation of the baroque (and broken) regulatory structure in the US. If my suspicion (b) is correct, going after middlemen attacks the symptom, not the cause, and the underlying problem will persist.

All that said, just as the case with foreign-benchmarked MFN pricing, it is naive to think that the direct purchase mandate will lead drug companies to reduce direct-to-consumer prices to the level they charge PBMs. The rules would totally change the negotiating dynamic between them. And again–and this is crucial–this is mainly about how monopoly rents will be distributed/split, not the amount of the rent (and thus not the final price to the consumer), which is driven by the underlying market power inherent in patent protected medicines.

In sum, I think this EO’s significance has been vastly overstated, because (a) it is essentially a “mission order” that sets out a broad objective, and the effects of which will be driven by the tortuous politicized rulemaking process required to carry it out, and (b) does not touch the underlying drivers of pharma prices.

Another major issue of the past few weeks is the (in Trump’s words) “Big Beautiful [budget] Bill” working its way through the House.

First off, let me say that it is almost certainly the case that nothing Big in government is really beautiful. Hell, who even knows what’s in it, precisely because it is so big? It be like “Yeah the chick in the burkha is really beautiful! And she’s actually a chick! Take my word for it!”

Its main attribute is that it will–if the legislative legerdemain works–mitigate the logrolling and secret last minute deals that corrupt the standard budgeting process. Mitigate, not fix.

The “beautiful” bill has some real warts. Hell, cancers, maybe. A sample.

  • An elevated state and local tax (SALT) exemption. Elevated so high as to be virtually non-binding. A sop to high income, high tax states which seriously undermines their incentives to control spending and taxation. If California, New York, Illinois, etc., want to raise taxes and spend more, let them fuck their own citizens, not the rest of us. Maybe that will force their citizens to get their minds right, and set their governments straight.
  • Serious backsliding on the rollback of Biden’s grotesque, and grotesquely named, “Inflation Reduction Act.” It should be terminated in its entirety, with extreme prejudice. But this bill–which mind you cannot bind future Congresses–delays implementation of subsidy cuts and mandates until four years from now, at the earliest.

Gee, why four years, I wonder?

The renewables subsidies and mandates make energy excessively costly in return for no meaningful environmental benefits. They are also unaffordable given America’s parlous fiscal situation.

Notably, Rumpublicans are among those pushing to save these monstrosities.

  • Virtually noting meaningful on entitlement reform. Even extremely modest changes to Medicaid have elicited shrieks and wails, and not just from Democrats.

The US fiscal situation is far and away the greatest danger our to economic prosperity and national security. But nobody–least of all Trump–is taking it seriously. Like Scarlett O’Hara, they will think about that tomorrow.

Except, apropos CCR, that day never comes.

So we seem destined–doomed–to go bankrupt like Hemingway’s Mike Campbell, “Gradually and then suddenly.”

DOGE and Musk held out the (false) promise of preventing this fate by attacking “waste and inefficiency.” Even if such massive inefficiencies exist, DOGE didn’t go through them like a buzzsaw: instead, DOGE has been buzzsawed and Elon has slunk away, achieving a dime on the promised dollar at the very most.

And at the outset, I expressed skepticism–though not enough–that the supposedly “easy” route of restoring fiscal sanity through attacking waste would actually work. The brutal fact is that without addressing entitlements we are on the highway to fiscal hell.

The most depressing takeaway is that the supposedly transformative and revolutionary Trump presidency is at most tinkering with an unsustainable status quo, and even that elicits frenzied, and indeed unhinged, opposition. The nation is as unserious about addressing its existential fiscal problems as was France in the 1780s, and just as politically poisonous.

And we know how that worked out.

15 Comments »

  1. Nice write up, as usual.
    The topic of drug costs in interesting. While not referring to the price at the pharmacy covering R&D, what is your opinion on a $10-$18 dollar single aspirin at the hospital?
    Simply an observation: why are Joe and Donald referred to by their family name, but Mrs Clinton is always Hillary?

    Comment by John Robert — May 19, 2025 @ 1:28 pm

  2. On the whole I despise man-in-the-pub Economics. In particular I despise the strange belief that everything can be cured by cutting out the middle man. For a while I wondered whether it was an anti-semitic trope but then I realised, no, it was just another symptom of the stupidity of m-i-t-p Economics.

    Comment by dearieme — May 19, 2025 @ 3:30 pm

  3. Patents and creative protection is a mess.
    It is ridiculous that a song can enjoy 70 years of protection when the man who sang it didn’t even write it.
    Do Picasso’s heirs (most of whom he conspicuously ignored) deserve the droit de suite every time one of his paintings changes hands?

    That said, patent protection is designed to stimulate invention.

    Compressing patent protection is not a good idea. The harma
    lobby is so powerful they will by pass stage 2,3,4 trials and release dangerous drugs on us.
    Better to give them a 25 year patent from approval instead of 25 years from application. The trials and publication will give any competitor plenty of time to develop a better solution but if the new product is really good it rewards the innovator for longer.

    (Full disclosure: I have a patent and wouldn’t have bothered the lawyers if I thought there was no money in it. A plumbing gadget doesn’t have to apply to the FDA so my time line is two or three years.)

    Comment by philip — May 19, 2025 @ 5:05 pm

  4. If the EU and Canada had to pay the full price of pharmaceuticals they would go bankrupt.

    Comment by MARK — May 19, 2025 @ 5:52 pm

  5. “Make maximalist demands, negotiate down from there” ” if you panicked, you were played”
    HOW are people still being surprised by this? (Myself included, I admit). Trump literally published a book saying that this is how he deals – we all really should be used to it.

    “This makes PBMs analogous to foreign governments”
    I think an interesting analysis would be why PBMs are not able to secure for their patients the kinds of discounts that foreign governments do. Given the size of the US, there are surely some deals where the PBM’s purchase volumes rival or exceed those of foreign government health systems (though maybe in saying that, I’m just re-stating the Profs point).

    “One interpretation is that these countries are free riding off the innovation paid for by US consumers who pay full fare.”
    I think there’s anecdotal evidence that US consumers are being overcharged as a target of opportunity, rather than being the sole supporting pillar of R&D costs: For example, US insulin (well out of patent protection) was until recently unreasonably expensive in the US. Same for hospital care: Developed countries with similar labour and capital costs can provide beds, paracetamol and nurses for a fraction of what US hospitals charge. I say you should let American consumers wield monopsony power, and see where the chips land. If it really is the case that R&D suffers, then for sure, adjust course – and you’ll probably find Europeans willing to along with that (our policies are to avoid getting screwed by business, not to force Americans to pick up the tab afterwards).

    Comment by HibernoFrog — May 20, 2025 @ 3:45 am

  6. Prof:

    Nice to see you drawing a parallel between the US of A and pre-“Après moi, le déluge” France.

    If only the nobility and the clergy had contributed their dimes to the tax coffers!

    I always thought the guillotine was a humane way of ending a life. Much more humane than firing squads or electric chairs and no comparison with the barbaric gas chamber or perverted lethal injection. So if the US of A gets a revolution when the fisc collapses and there’s a Reign of Terror (whether from the Right or the Left), one hopes the guy (or gal) in charge will possess the common humanity to introduce the guillotine as the preferred method of executing the regime’s enemies.

    Now who do we know who would make a great latter-day Saint-Just?

    Comment by Simple Simon — May 20, 2025 @ 4:07 am

  7. Deficit is the largest worry and the larger worry is the lip service being paid to it without the action of doing anything about it. When we go broke, we know who will be at fault. The American taxpayer.

    Comment by Jeff Carter (@pointsnfigures1) — May 20, 2025 @ 6:08 am

  8. In any discussion truth co-exists with lies, but there are always some examples that are so egregious as to cause nausea.

    The pharma racket is fraught with examples of $0.25 to make drugs that sell for $1,000.

    It is disgusting. I do not know how a pharma CEO or boardmember sleeps at night with such a predatory action on his conscience.

    I have been buying drugs in Canada for decades and pay right at 23% of US prices. Recently there have been some US “specials” that are actually better than Canadian prices which surprises me.

    The whole pharma racket could be right priced by a decent accountant in an afternoon. It’s obvious.

    JLM
    http://www.themusingsofthebigredcar.com

    Comment by Jeffrey Minch — May 20, 2025 @ 9:39 am

  9. “$0.25 to make drugs that sell for $1,000.” When you grow up, Mr Minch, I hope you’ll see that that’s a pretty dim-witted point.

    Comment by dearieme — May 20, 2025 @ 4:04 pm

  10. Re: Triple B (bill). I have that sinking feeling, too. So much effort extended to elect this Admin – and it looks more and more this mountain has delivered a mouse. Agree about DOGE, too.
    I’m at a loss how to prep for the – now seemingly inevitable – for what’s coming.

    Comment by Tatyana — May 23, 2025 @ 7:11 pm

  11. Finally!! My, how the penny has dropped, and with an enormous clunk. So all what’s happened this year was just a bullsh*t preamble to delivering a big payout to his backers, courtesy of unborn US taxpayers? I’m shocked I tell you, shocked to the core….

    DOGE was a grift too, no real intent to do anything more than cull a few ideological targets purely for the benefit of his base. The only organisation of note which really has been pared back to a shadow of its former self is err Tesla.

    @deari – So I take it you’re not a fan of Farage, the ultimate practitioner of man-in-the-pub Economics (+ just about every other subject he comments on)? Just like Trump, part of me would love to see him and his ramshackle tribe elected here, just to see how catastrophically useless they’d be in government. It truly would be something to behold.

    @Tatyana – mwhahahaha!! Another one for the scrapbook!

    Comment by David Mercer — May 24, 2025 @ 1:36 am

  12. Also I’m reading that the EU has just been threatened with further tariffs (presumably after those in the administration have taken up appropriate short positions). I wonder if this has anything to do with the bloc agreeing a minerals deal with Greenland? Gotta love those cheeky Greenlanders, acting in their own sovereign interests.

    Comment by David Mercer — May 24, 2025 @ 1:50 am

  13. apropos promises vs delivery, in other aspects:
    https://raconteurreport.blogspot.com/2025/05/kash-is-klunker.html, with this encompassing characteristic in the thread:
    “This is only tangentially about Cheetoh Jesus, and far more about the douchebags he keeps picking to fill the posts, all of whom turn into the most controlled-opposition do-nothings and incompetents ever seen in the nation’s history. It’s like every time he goes lion shopping, he comes home with a 20-pound aging tomcat who got “fixed” by the vet, and can barely muster the strength to flop face-first into his food bowl twice a day.”

    Comment by Tatyana — May 24, 2025 @ 1:29 pm

  14. @tatyana Well if you didn’t see that coming back in November, you really were played. As I said back then, the incoming circus was rapidly morphing into a freakshow. It was clear to see for those without blinkers and superstrong rose-tinted lenses.

    Absolutely lovin’ all this buyers remorse

    Comment by David Mercer — May 25, 2025 @ 2:18 am

  15. “Absolutely lovin’ all this buyers remorse”

    https://www.wakeuptopolitics.com/p/the-myth-of-the-regretful-trump-voter
    https://lavocedinewyork.com/en/news/2025/04/17/polling-guru-no-buyers-remorse-if-election-was-today-trump-would-still-win/

    From the guy living in Keir Starmer’s England.
    https://www.telegraph.co.uk/news/2024/10/12/keir-starmers-first-100-days-have-been-a-disaster/
    https://www.youtube.com/watch?v=_bri28eJtag

    Meanwhile, let’s all help David celebrate the release of Tommy Robinson.
    https://www.express.co.uk/news/uk/2060460/tommy-robinson-released-jail-early

    Comment by Pat Frank — May 31, 2025 @ 8:48 am

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